Nanocomposites and nanomaterials
Inactivation of adenoviruses using titanium dioxide nanoparticles 
Pankivska Yu. 1, Biliavska L., 1 Povnitsa O., 1 Zagorniy M. 2, Ragulya A.2 Zagorodnya S1, 
1 Zabolotny Institute of Microbiology and Virology, National Academy of Science of Ukraine, . Zabolotnogo str., 156, Kyiv-03143, Ukraine. 
E-mail: svetazagorodnya@ukr.net 
2 M. Frantsevich Institute for Problems of Materials Sciences . Krzhizhanovskoho St., Kyiv-03680, Ukraine

UV disinfection of drinking water is becoming more common as other typical water desinfection techniques cause the production of toxic byproducts [1]. While most organisms are readily inactivated by UV, certain viruses require a large fluence for adequate disinfection. Nanoparticles represent a major group of nanomaterials used in scientific researches, industry and commercial field [2]. As a result, nanoparticles have occupied an important place in antiviral therapy. Firstly, nanoparticles were used as drug delivery agents. Later, nanoparticles were functionalized with different types of biomolecules and drugs. In the current study titanium dioxide nanoparticles were analyzed for their capability to enhance the UV disinfection of human adenovirus.
Nanopowders of titanium dioxide (TiO2 (I) and TiO2 (II) with particle size and specific surface of 8-15 nm and 100 m2/g, and 20-30 nm and 50 m2/g respectively) and commercial TiO2 p25 were inves. It was found that the nanopowder (I) of the sample with particles of smaller size was more active after a shorter contact time (5 min) with virus. It has been established that the virucidal action of nanoparticles increases by 30% when using ultraviolet irradiation. The obtained results confirm the potential use of titanium dioxide nanoparticles for the synthesis of inactivating compounds with disinfecting activity and their subsequent use as components of filters for water and air disinfection.

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