"Nanotechnology and nanomaterials"

Complexing of Fullerenes C60 and C70 with Some Metal Lactates: 
Design and Synthesis

O.V. Мykhailenko1, А.V. Strungar2, Yu.I. Prylutskyy1, І.V Кomarov1,  O.O. Мykhailenko1, O.Yu. Lagerna1

1Taras Shevchenko National University of Kyiv, 64, Volodymyrska Str., 
01601 Kyiv, Ukraine, alexm-@ukr.net

2Vernadsky National Library of Ukraine, 3, Holosiivskyi ave.,
03039 Kyiv, Ukraine

Within this framework, we suggest using Mg2+, Ca2+, Sr2+, Zn2+ as a strong complexing agents, with lactic acid anion and fullerenes С60 and C70 as ligands. 
We have performed a quantum-chemical analysis of possible complexing of MetLac2 (Met = Mg2+, Ca2+, Sr2+, Zn2+) with fullerenes С60 and C70, using ММ+, РМ3 and Monte-Carlo methods. There has been calculated the optimal structures, absorption spectra of С60 and C70 with various amounts of MetLac2 on the spherical surface of the latter. There has been found a constant of complex’s stability which is 68.5 l·mol-1; 55.3 mol-1; 98.5 l·mol-1; 108.2 l·mol-1 in accordance (kkorr  0,98). 
There has been obtained the aqueous solutions of complexes of fullerenes with lactates of the specified metals. There are has been detected their anti-ischemic activity in vivo experiments.

1.	S.R. Petrusenko, Ya.O. Vitushinska, V.V. Trachevsky, O.V. Mykhailenko. Direct synthesis of some transition metal lactates. Kyiv, 2017, p. 124.
2.	О.V. Мykhailenko, Yu.I. Prylutskyy, І.V. Кomarov, А.V. Strungar, О.O. Мykhailenko. SWCNT-based carcerplex: molecular containers for unstable compounds. Kyiv, 2017, p. 15.