Nanobiotechnology for health-care

Application of natural oils in assembly of topical 
formulations for health-care products
Waglewska E., Bazylińska U.
Faculty of Chemistry, Wroclaw University of Science and Technology, Poland. Wybrzeze Wyspianskiego, 27, 50-370 Wroclaw, Poland.
E-mail: urszula.bazylinska@pwr.edu.pl

Recently, there is a scientific and technological interests in application of natural raw materials as biodegradable oils, emulsifiers and natural additives to fabricate biocompatible formulations, i.e. emulsions, nanoemulsions or liposomes with successful application in cosmetics and pharmaceutical industry - the fastest growing sectors of consumer goods. Self-assembled surfactant structures, including topical emulsions provide almost endless opportunities in the area of health-care products and thus have rapidly become the subject of many research, due to their high kinetic stability, non-toxicity and a very good ability to solubilize active ingredients with different size, surface charge and hydrophobicity [1,2].
For this reason, the main goal of our research was to design new topical formulations stabilized by natural raw biomaterials, i.e. mango, olive, sesame, watermelon seed and refined sweet almond oils. Their physicochemical properties were also determined as the basis for the potential launch of placing on the health-care products market. The application of multiple light scattering permitted for rapidly identification of the developed emulsions instabilities. This method showed that the preparation containing refined sweet almond oil was the most stable of all the products. Considering the results pH obtained, all formulations designed could be applied for possible dermal application. 

Acknowledgements: This work has been supported by National Science Centre (Poland) within a framework of SONATA 8 programme (No.2014/15/D/ST4/00808).

1.	Otto A., du Plessis J., Wiechers J.W. Formulation effects of topical emulsions on transdermal and dermal delivery // Int J Cosmet Sci.- 2009.-31.-P. 1-19.
2.	Madaan V., Chanana A., Kataria M.K., Bilandi A. Emulsion technology and recent trends in emulsion applications // Int Res J Pharm.-2014.-5.-P. 533-542.