Nanochemistry and biotechnology
Toxic Effect of Morpholine-Functioned Calix[4]arene Nanofibers on MCF-7 Breast Cancer Cells 
 Ertul S.1, Ozcan F.1,2
1 Department of Chemistry, Faculty of Science, Selcuk University
2Advanced Technology Research and Application Center, Selcuk University, 42075 Konya, Turkey
sertul42@gmail.com & fatihzcan06@gmail.com
Ring-shaped basket should be similar structure and preparation of unlimited derivatives to be of the calixarenes used in different areas. These new features are gained; ion selective electrode construction, column filling material, as a sensor, as chiral and aciral catalyst, in membrane studies, enzyme-mimic and ion, Fe3O4 magnetic nanoparticles and as a molecule carrier were immobilized [1]. In recent years in nanotechnology it was observed that the effective area was increased polymerisation of polymers by the production of nanofibers by electrospin method of polymeric materials.  Fibers obtained from large molecular weight structures different characteristics are emerging diameters drop from micrometers to nanometers. Some of them are like these, high surface area / volume ratio, ımproved surface properties, better mechanical performance than any known material form. These properties include nanofibers makes one of the optimum candidates for many important application areas[2,3]. In this study, the effect of p-tert-butylcalixarene compound with Morpholine group on MCF-7 cancer cell was examined by electrospinning the nanofiber using a 15 mm diameter ITO surface.

1.  Ozcan F., Bayrakci  M., Ertul S. Synthesis and Preparation of Novel   Magnetite NanoparticlesContaining Calix[4]arenes With Different Chelating Group Towards Uranium Anions // Journal of Macromolecular Science-2015.-Part A 52.-P. 599–608. 
     2. Ozcan F., Bayrakci M., Ertul S. Synthesis and characterization of novel         nanofiber based calixarene and its binding efficiency towards chromium and   uranium ions // J Incl. Phenom Macrocycl Chem.-2016.- 85.-P.49–58.
     3. Mokhtari B, Pourabdollah K. Bioactive nanofibers: synergistic effects of nanotopography and chemical signaling on cell guidance //J Incl Phenom Macrocycl Chem.- 2012.- 73. –P. 1–15.