Nanostructured surfaces

Nanostructured gold microelectrodes for nonenzymatic glucose sensing
Hovancová J.1, Šišoláková I.1, Oriňaková R.1, Petruš O.1, Shepa I.2
1Department of Physical Chemistry, University of P.J. Šafárik in Košice, Moyzesova 11, 040 01 Košice, Slovakia
2Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia 
E-mail: jana.hovancova@student.upjs.sk

Gold is frequently used and well-studied electrode material for the development of nonenzymatic glucose sensors due to its great catalytic properties [1]. The main advantage of gold is the ability to detect glucose in both neutral and alkaline solution. Moreover, nanostructured gold enlarges accessible surface area and enhances mass transport behavior [2]. Furthermore, the usage of gold microelectrode makes a contribution to the miniaturization of the electrochemical system. The modification of gold microelectrodes by inverse opal nanostructure results in the very suitable electrode material for glucose sensing. Electrode material morphology was studied by scanning electron microscopy and atomic force microscopy and electroanalytical properties were studied via cyclic voltammetry. The modification of gold microelectrodes resulted in an increase in surface area and the highly ordered and homogenous electrode surface. Nanostructured gold microelectrodes display wide linear range comparable with other gold electrode materials, low detection limit and high sensitivity. The common interfering species were used to consider the microelectrodes application in clinical practice. 

1. 	Guo, X., Deng, H., Zhou, H., Fan, T., Gao, Z. Detection of glucose with a lamellar-ridge architectured gold modified electrode// Sensors Actuators, B Chem. -2015.-206.-P. 721–727. 
2. 	Shu, H., Cao, L., Chang, G., He, H., Zhang, Y., He, Y. Direct electrodeposition of gold nanostructures onto glassy carbon electrodes for non-enzymatic detection of glucose// Electrochim. Acta -2014.- 132.- P. 524–532.