Thematic area of my work (Nanochemistry and biotechnology)
Nanobasket, Calixarenes : in Biocatalysis Studies
Mustafa Yilmaz
Selcuk University, Department of Chemistry, 42075, Konya, Turkey          E-mail: myilmaz@gmail.com

 Calixarenes have become important receptors in synthesis and applications as supramolecular platforms for molecular recognition, sensing and self-assembly, catalysis, biocatalysis, nanotechnology, and drug discovery. Because of their unique molecular structure, calixarenes have been used as promising materials which could take a prominent place such as development of mimic biocatalysts, enhancing catalytic activity and enantioselctivity of enzymes, and providing organic/water solubility to the reagents for several enzyme-dependent biological reactions [1,2]. 
In this study, iron magnetic nanoparticles capped with fluorescent calixarene derivatives (Fe3O4@Calix-2 and Fe3O4@Calix-3) were prepared in one-step using coprecipitation of Fe(II) and Fe(III) in basic solution. Different techniques were used to characterize the synthesized magnetic nanoparticles, such as Fourier Transform Infrared spectroscopy (FTIR), powder X-ray diffraction (XRD), vibrating sample magnetometer (VSM) and confocal microscopy. 
Enzyme was encapsulated on synthesized nanoparticles following sol–gel method. The results showed that encapsulated lipases nanoparticle with calixarene moieties lead to increased activity, stability, reusability and enhanced stereoselectivity in kinetic resolution.

1.	Yilmaz M., Sayin S. Calixarenesin Organo and Biomimetic Catalysis. In: Neri P., Sessler J., Wang MX. (eds) Calixarenes and Beyond. Springer, Cham., 2016.  P.219-242.
2.	Karakurt, S., Kellici, T.F., Mavromoustakos, T., Tzakos A.G., Yilmaz, M., Curr. Org. Chem., 2016, 20, 1043-1057 // Curr. Org. Chem.-2016, -20, 1043-1057.