Nanobiotechnology for health-care

Atheroma regression with intermittent pneumatic compression
Vasylyuk S.V.1, Zaitsev D.V.2
1Kiyv national Taras Shevchenko university, Physics faculty,  Volodymyrska str., 60, Kyiv-09102, Ukraine. 
E-mail: svetlanafvasylyuk@server.com
2Kundiiev Institute of Occupational Health of the NAMS of Ukraine, 75 Saksagansky str., Kyiv, 01033, Ukraine.

Intermittent pneumatic compression (IPC) is used in patients with peripheral arterial disease and critical ischemia for its ability to increase arterial blood flow and having benefit on plasma lipids. We predicted that, under compensated lipids ratio, IPC can promote the resorption of cholesterol deposits within 1.5-3 years [1].
A 54-year-old woman was admitted with complaints of frequent episodes of dizziness. The patient followed a diet, took omega-3 drugs and had a regular aerobic activity. An ultrasound examination revealed atheromas in the arteria carotis bifurcation, up to 10% on the right, and 30% on the left. IPC procedures lasting 72 minutes were carried out once a week for two years with no additional treatment. Each of 10 chambers was inflated for 1 s with the pressure 50 mm Hg. Two years later, an ultrasound scan was performed again by the same doctor and device. Atheromas decreased on the right up to 5% and on the left up to 25%.
The formation of stable laminar blood flow changes the expression of shear-dependent genes of endothelial cells to anti-inflammatory and anti-atherogenic [2]. Surface contacts augmentation leads to acceleration of cholesterol molecular transport, macrophage and endothelial progenitor cells migration [3].
The paper considers the approach of pulse waves modelling using soliton theory. The basic idea is that the real pulse wave nature is very similar to the properties of solitons. The central role is played by the elastic interaction properties between solitons and solitons with local perturbations.

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