Nanochemistry and biotechnology

New hybrid sensing platform for simultaneous optical and electrochemical biosensing applications 

V.M. Pyeshkova1,2, O.O. Soldatkin1,2, V.I. Chegel2,3, S.V. Dzyadevych1,2

1 Institute of Molecular Biology and Genetics of NAS of Ukraine, Department of Biomolecular Electronics, Zabolotnogo Street 150, 03680 Kyiv, Ukraine;
E-mail: victoriya.p@gmail.com
2 Institute of High Technologies of Taras Shevchenko National University of Kyiv, Hlushkova Avenue, 4g, 03022, Kyiv, Ukraine;
3 V.E. Lashkaryov Institute of Semiconductor Physics, National Academy of Sciences of Ukraine, 41, Nauki Avenue, Kiev 03028, Ukraine

The hybrid opto-electrochemical sensing devices can have a lot of advantages combining of capabilities of electrochemical and optical measurements. Combination of two different methods can significantly improve biosensor analytical characteristics (sensitivity, limits of detection etc.).
 In this work two pairs of planar thin-film interdigitated gold electrodes, deposited on a transparent glass plate (5 * 30 mm) and modified by gold nanoparticles was used as a transducer. The fabricated transducer can be used as a hybrid sensing platform for simultaneous optical (based on localized surface plasmon resonance) and electrochemical biosensing applications. The analytical characteristics of gold electrodes modified by gold nanoparticles were studied and compared with unmodified gold electrodes. The work of modified and unmodified electrodes with immobilized biomaterial was investigated. According to the obtained results it was shown that modification of electrodes surfaces with gold nanoparticles is perspective for hybrid opto-electrochemical biosensor fabrication.
This work was supported by the National Academy of Sciences of Ukraine “Smart sensor devices of a new generation based on modern materials and technologies".