Physico-Chemical nanomaterials science

Influence of presence of vitamins B2, B3, B9, and C on calcium oxalate monohydrate crystallization processes in simulated body fluid
Dryhailo M.K.1, Taranets Y.V.2, Pritula I.M.2
1 V.N.Karazin Kharkiv National University, Faculty of Physics.
Svoboda Sq., 4, Kharkiv-61000, Ukraine. 
E-mail: mkdryhailo25@gmail.com
2 Institute for Single Crystals NAS Ukraine, Department of Non-linear Optics. 
Prospekt Nauki, 60, Kharkiv-61000, Ukraine.

One of the most wide-spread diseases in the world is urolithiasis. Crystals of organic and, especially, mineral origin have the propensities for the formation of kidney stones. The reviewed example of these crystals is calcium oxalate monohydrate (COM) [1]. Many scientists are interested in the influence of adding different components such as amino acids, vitamins etc. on COM crystallization processes [2].
The purpose of this work is showing the influence of the presence of water-soluble vitamins B2, B3. B9, and C on the phase of nucleation, structure, morphology, and size of COM in simulated body fluid. The temperature during the experiment was 37°C, I = 0,15 (NaCl), pH = 5,8. 
The phase composition and structure of COM were analyzed applying X-ray diffractometry and FTIR-analysis. The crystallization kinetics for the model COM solutions was studied by measuring the solution turbidity. The morphology and size of obtained crystals were examined using scanning electron microscopy. 

1.	Rez P. What does the crystallography of stones tell us about their formation? // Urolithiasis. - 2017.-45(1) - P. 11-17.
2.	Taranets Y. V. et al., Effect of amino acids and B-group vitamins on nucleation of calcium oxalate monohydrate crystals // Journal of Crystal Growth. - 2020.-531, 125368.